New cannabinoid found with thirty-fold the potency of THC

Researchers at Italy’s University of Salento have discovered two new cannabinoids – THCP and CBDP – and THCP could be more potent than THC, according to a study published on Nature. In tests on mice, researchers found that THCP showed “an affinity for CB1 receptor more than thirty-fold higher compared to the one reported for THC.” 

The other compound – CBDP – reportedly doesn’t bind well to CB1 or CB2 receptors which doesn’t make the cannabinoid a priority for further research; however, the researchers said that THCP “should be included in the list of the main phytocannabinoids to be determined for a correct evaluation of the pharmacological effect of the cannabis extracts administered to patients.”

According to the study, new research will continue to test how THCP cannabinoid acts as an antioxidant, anti-inflammatory and anti-epileptic activity – the health benefits most associated with CBD.

The research brings the total number of discovered cannabinoids in the cannabis plant to 150, though the researchers note that “most of them have neither been isolated nor characterized.”

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